3-Chloro-4-fluorobenzyl alcohol

3-Chloro-4-fluorobenzyl alcohol - Names and Identifiers

Name	3-Chloro-4-fluorobenzyl alcohol
Synonyms	RARECHEM AL BD 0222 (3-Chloro-4-fluorophenyl) 3-Chloro-4-fluorobenzylaalcohol 3-CHLORO-4-FLUOROBENZYL ALCOHOL 3-Chloro-4-fluorobenzyl alcohol 3-Chloro-4-fluorobenzenemethanol (3-chloro-4-fluorophenyl)methanol (3-CHLORO-4-FLUORO-PHENYL)-METHANOL
CAS	161446-90-8
EINECS	642-649-8
InChI	InChI=1/C7H6ClFO/c8-6-3-5(4-10)1-2-7(6)9/h1-3,10H,4H2

3-Chloro-4-fluorobenzyl alcohol - Physico-chemical Properties

Molecular Formula	C7H6ClFO
Molar Mass	160.57
Density	1.344
Boling Point	243℃
Flash Point	100℃
Water Solubility	Slightly soluble in water.
Vapor Presure	0.0183mmHg at 25°C
pKa	13?+-.0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5355
MDL	MFCD01631550

3-Chloro-4-fluorobenzyl alcohol - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class	IRRITANT

3-Chloro-4-fluorobenzyl alcohol - Introduction

3-choro-4-fluorobenzyl alcohol is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: 3-chroo-4-fluorobenzyl alcohol is a colorless to slightly yellow liquid.
2. Melting Point:-3 ℃.
3. Boiling point: 135-136 ℃.
4. Density: 1.37g/cm³.
5. Solubility: 3-Chloro-4-fluorobenzyl alcohol is less soluble in water and soluble in most organic solvents.

Use:
1. 3-Chloro-4-fluorobenzyl alcohol can be used as an intermediate in organic synthesis and plays an important role in the manufacture of drugs and pesticides.
2. It can also be used to prepare some surfactants, flame retardants, dyes and coatings.

Method:
3-Chloro-4-fluorobenzyl alcohol can be prepared by the reaction of chlorobenzene and silver tetrafluoroacetate. The specific steps are as follows:
1. Add chlorobenzene and silver tetrafluoroacetate to the reaction bottle, and add the solvent.
2. Heat the reaction flask and react at an appropriate temperature.
3. After the reaction is completed, the target product is extracted by distillation.

Safety Information:
1. 3-Chloro-4-fluorobenzyl alcohol may have irritating effects on human skin, eyes, respiratory tract and digestive system, and contact should be avoided.
2. During use, attention should be paid to establishing a good ventilation system and wearing appropriate protective equipment, such as gloves, protective glasses and respiratory protection.
3. In case of ingestion, aspiration or skin contact, rinse immediately with water and seek medical help.
4. Should be stored in a cool, dry, well-ventilated place, away from fire and oxidant.

Last Update：2024-04-09 15:17:53